Efflux pumps are involved in the Gram negative bacterial defense against 1 isobavachalcone and diospyrone , two natural products
نویسندگان
چکیده
1 Department of Biochemistry, Faculty of science, University of Dschang, P.O. Box 67 8 Dschang, Cameroon; 9 2 Department of Pharmacy and Traditional Pharmacopoeia, Faculty of Medicine and 10 Biomedical Science, University of Yaoundé I, P.O. Box. 8664, Yaoundé, Cameroon; 11 3 Department of Organic Chemistry, Faculty of science, University of Yaoundé I, P.O. Box 12 812 Yaoundé, Cameroon 13 4 Transporteurs Membranaires, Chimiorésistance et Drug design, UMR-MD1, IFR 88, 14 Université de la Méditerranée, Facultés de Médecine et de Pharmacie, 27 Bd Jean Moulin, 15 13385 Marseille cedex 05-France 16
منابع مشابه
Efflux pumps are involved in the defense of Gram-negative bacteria against the natural products isobavachalcone and diospyrone.
The activities of two naturally occurring compounds, isobavachalcone and diospyrone, against documented strains and multidrug-resistant (MDR) Gram-negative bacterial isolates were evaluated. The results indicated that the two compounds exhibited intrinsic antibacterial activity against several Gram-negative bacteria, and their activities were significantly improved in the presence of an efflux ...
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